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TytoAlba95
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Source: paper
When the cells were transfected with miRNA-mimic it increased the miRNA expression. Is this increase due to the activity of RNA-dependent RNA polymerase, which generates secondary miRNAs?
Last edited:
Source: paper
There are several possible reasons for increased miRNA expression in diseases. One theory is that the body may produce more miRNA in response to stress or injury. Another possibility is that certain miRNAs may be involved in regulating gene expression and can become dysregulated in diseases.
Yes, studies have shown that environmental factors such as diet, pollutants, and stress can influence miRNA expression. These factors can alter the levels of specific miRNAs, which may contribute to the development of diseases.
MiRNAs have been found to play a significant role in cancer development and progression. They can act as either tumor suppressors, inhibiting cancer growth, or oncogenes, promoting cancer growth. Changes in miRNA expression have also been linked to drug resistance in cancer treatment.
Research has shown that miRNA expression levels can change with age. Some miRNAs have been found to decrease with age, while others increase. These changes in miRNA expression may contribute to the aging process and age-related diseases.
Yes, miRNA expression can potentially be used as a diagnostic tool for certain diseases. Studies have shown that specific miRNAs are dysregulated in various diseases, and measuring their expression levels can aid in diagnosis. However, more research is needed before miRNA expression can be used routinely in clinical settings.